CHEME7900 Seminar: Chelsea Hu, Ph.D. '18 (Texas A&M)

Closing the Loop on Synthetic Biology: Multiscale Modeling and Feedback Control of Living Systems Synthetic biology has made it possible to program cells with increasingly sophisticated genetic circuits, yet these circuits rarely operate in isolation. They are embedded in growing, resource-limited cells whose physiology changes over time and across environments. This coupling between circuit function and host dynamics creates both challenges and opportunities for biological design. In this seminar, I will discuss my group’s efforts to understand and control synthetic gene circuits as multiscal